Description Stevens-Johnson Syndrome is a rare syndrome that occurs due to skin and mucous membranes provide excessive reaction to a drug or infection. Often if an attack occurs the patient should be rushed to hospital for treatment, while the recovery period could take weeks. If very severe disease can result in death.
Symptom This syndrome begins with flu-like symptoms such as fever and sore throat, followed by red or purplish rash on the skin that feels pain and spread or even a blister. In many cases, the cells in the outermost layer of skin will die so that her skin like peeling off.
Cause Stevens-Johnson syndrome is triggered by the use of most drugs, although some people can also be triggered by infection with certain bacteria. But sometimes, the exact cause is not always certain that it is difficult to prevent.
True allergic reactions caused by substances that enter the body considers it is a foreign body that will cause an antibody reaction in the body.
"All the drugs can actually trigger allergic responses are called hypersensitivity reactions, but everyone has different reactions," says Dr. Dante Saksono H SpPD, when contacted detikHealth PhD.
Types of drugs most often triggered Stevens-Johnson syndrome, among others, are as follows, as quoted from MayoClinic, Thursday (06/16/2011).
Drug-drug anti-gout, for example allopurinol
Drugs Non-Steroid Anti Inflammatory (NSAID) that is widely used to relieve pain
Antibiotics, especially penicillin
Anticonvulsants, usually used by people with epilepsy.
Meanwhile, the infectious germs that could trigger it are as follows.
Herpes (herpes simplex or herpes zoster)
Influenza
HIV
Diphtheria
Typhoid
Hepatitis
In certain cases, Stevens-Johnson syndrome can also be triggered by physical stimuli such as radiaoterapi and ultraviolet light.
Treatment First aid to overcome the allergy drug in Stevens-Johnson Syndrome is to stop taking drugs that trigger allergies. Next is to give allergy medications (antihistamines) to relieve symptoms, or corticosteroids if symptoms are severe enough.
Adjunctive therapy given at the hospital include rehydration or replacement of lost body fluids by using the infusion. If injury occurs, the layer of dead skin must be cleaned and then covered with a bandage wound to avoid infection.
source: detikHealth.com
Symptom This syndrome begins with flu-like symptoms such as fever and sore throat, followed by red or purplish rash on the skin that feels pain and spread or even a blister. In many cases, the cells in the outermost layer of skin will die so that her skin like peeling off.
Cause Stevens-Johnson syndrome is triggered by the use of most drugs, although some people can also be triggered by infection with certain bacteria. But sometimes, the exact cause is not always certain that it is difficult to prevent.
True allergic reactions caused by substances that enter the body considers it is a foreign body that will cause an antibody reaction in the body.
"All the drugs can actually trigger allergic responses are called hypersensitivity reactions, but everyone has different reactions," says Dr. Dante Saksono H SpPD, when contacted detikHealth PhD.
Types of drugs most often triggered Stevens-Johnson syndrome, among others, are as follows, as quoted from MayoClinic, Thursday (06/16/2011).
Drug-drug anti-gout, for example allopurinol
Drugs Non-Steroid Anti Inflammatory (NSAID) that is widely used to relieve pain
Antibiotics, especially penicillin
Anticonvulsants, usually used by people with epilepsy.
Meanwhile, the infectious germs that could trigger it are as follows.
Herpes (herpes simplex or herpes zoster)
Influenza
HIV
Diphtheria
Typhoid
Hepatitis
In certain cases, Stevens-Johnson syndrome can also be triggered by physical stimuli such as radiaoterapi and ultraviolet light.
Treatment First aid to overcome the allergy drug in Stevens-Johnson Syndrome is to stop taking drugs that trigger allergies. Next is to give allergy medications (antihistamines) to relieve symptoms, or corticosteroids if symptoms are severe enough.
Adjunctive therapy given at the hospital include rehydration or replacement of lost body fluids by using the infusion. If injury occurs, the layer of dead skin must be cleaned and then covered with a bandage wound to avoid infection.
source: detikHealth.com
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Agus Kurniawan - Wednesday, June 22, 2011